University of Pittsburgh PITT HOME  |  FIND PEOPLE  |  CONTACT US  
 
Health Sciences @ Pitt   |    UPMC   |    HSLS   |    School of Medicine   |    Health Sciences Calendar   |    Our News & Events  
 
HOME
ABOUT US
FACULTY
CLINICAL TRAINEES
RESEARCH TRAINEES
ATTENTION ALUMNI
RESIDENCY PROGRAM
RESIDENT WEBSITE
CONFERENCES
EVENTS
CORNEA FELLOWSHIP PROGRAM
GLAUCOMA FELLOWSHIP PROGRAM
NEURO-OPHTHALMOLOGY FELLOWSHIP PROGRAM
ORBITAL, OCULOPLASTICS AND AESTHETIC SURGERY FELLOWSHIP
PEDIATRIC OPHTHALMOLOGY FELLOWSHIP PROGRAM
RETINA FELLOWSHIP PROGRAM
CLINICAL RESOURCES
VISUAL DIAGNOSTICS, IMAGING & LASERS
OPHTHALMOLOGY RESEARCH
RESEARCH LABORATORIES
CORE RESEARCH FACILITIES
GIVING & DEVELOPMENT
LECTURE SCHEDULE
LINKS
EMPLOYMENT OPPORTUNITIES
NEWS & AWARDS
Faculty
divider bar
 
19Hendricks.jpg Robert L. Hendricks, PhD
Joseph F. Novak Endowed Chair
Professor and Vice-Chair for Research
Director, Ophthalmology & Visual Sciences Research Center
Departments of Ophthalmology, Immunology, Microbiology and Molecular Genetics and Biochemistry
University of Pittsburgh School of Medicine

Eye and Ear Institute, Room 922
203 Lothrop Street
Pittsburgh, PA 15213
Phone: 412-647-5754
Email: hendricksrr@msx.upmc.edu
Fax: 412-647-5880
Faculty Research Interests
 
bullet point  Research Interests
a dividing bar
Viral Immunology Laboratory

 
bullet point  Education
a dividing bar
University of Illinois at Chicago, BS, Biology

University of Illinois at Chicago, MS, Microbiology

University of Illinois at Chicago, PhD, Immunology

 
bullet point  Academic Affiliation
a dividing bar
Professional Experience

1998 - present: Professor and Vice-Chair for Research, Department of Ophthalmology, University of Pittsburgh,Pittsburgh, PA

1998 - present: Director, Ophthalmology and Visual Sciences Research Center, University of Pittsburgh, Pittsburgh, PA

1998 - present: Professor, Department of Molecular Genetics and Biochemistry

1998 - present: Member, University of Pittsburgh Cancer Institute

2002 – present: Professor, Department of Immunology, University of Pittsburgh,Pittsburgh, PA

2002 – present: Member, McGowan Institute for Regenerative Medicine, University of Pittsburgh,Pittsburgh, PA

2004-present: Vice-Chair for Research, Department of Ophthalmology,University of Pittsburgh,Pittsburgh, PA

 
bullet point  Publications
a dividing bar
Select Recent Publications

1.St. Leger, A.J., Peters, B., Sidney, J., Sette, A., and Hendricks, R.L.:Defining the herpes simplex virus-specific CD8+ T cell repertoire in C57BL/6 mice. J. Immunol. 186: 3927-3933, 2011

2.Frank, G. M., A. J. Lepisto, M. L. Freeman, B. S. Sheridan, T. L. Cherpes, and R. L. Hendricks. 2010. Early CD4(+) T cell help prevents partial CD8(+) T cell exhaustion and promotes maintenance of Herpes Simplex Virus 1 latency. J.Immunol. 184:277-286.

3. Sheridan, B. S., T. L. Cherpes, J. Urban, P. Kalinski, and R. L. Hendricks. 2009. Reevaluating the CD8 T-cell response to herpes simplex virus type 1: involvement of CD8 T cells reactive to subdominant epitopes. J.Virol. 83:2237-2245. PMC 2643732

4. Knickelbein, J. E., K. M. Khanna, M. B. Yee, C. J. Baty, P. R. Kinchington, and R. L. Hendricks. 2008. Noncytotoxic lytic granule-mediated CD8+ T cell inhibition of HSV-1 reactivation from neuronal latency. Science 322:268-271. PMC 2680315

5. Cherpes, T. L., J. L. Busch, B. S. Sheridan, S. A. Harvey, and R. L. Hendricks. 2008. Medroxyprogesterone acetate inhibits CD8+ T cell viral-specific effector function and induces herpes simplex virus type 1 reactivation. J.Immunol. 181:969-975. PMC 2553693

6. Freeman, M. L., B. S. Sheridan, R. H. Bonneau, and R. L. Hendricks. 2007. Psychological stress compromises CD8+ T cell control of latent herpes simplex virus type 1 infections. J.Immunol. 179:322-328. PMC 2367250

7. Sheridan, B. S., K. M. Khanna, G. M. Frank, and R. L. Hendricks. 2006. Latent virus influences the generation and maintenance of CD8+ T cell memory. J.Immunol. 177:8356-8364. PMC 2366996

8. Decman, V., P. R. Kinchington, S. A. Harvey, and R. L. Hendricks. 2005. Gamma interferon can block herpes simplex virus type 1 reactivation from latency, even in the presence of late gene expression. J.Virol. 79:10339-10347. PMC 1182646

9. Xu, M., A. J. Lepisto, and R. L. Hendricks. 2004. CD154 signaling regulates the Th1 response to herpes simplex virus-1 and inflammation in infected corneas. J.Immunol. 173:1232-1239.

10. Khanna, K. M., R. H. Bonneau, P. R. Kinchington, and R. L. Hendricks. 2003. Herpes simplex virus-specific memory CD8+ T cells are selectively activated and retained in latently infected sensory ganglia. Immunity 18:593-603.
 
bullet point  Grants
a dividing bar
P30 EY08098-20 Hendricks (PI & Module Director) 04/01/89-03/31/14
NIH/NEI
“Core Grant for Vision Research”
The Core Grant will provide support for the following centralized research modules: Hybridoma/Tissue Culture; Molecular Biology; Electronic Shop; and Morphology & Image Analysis

T32 EY017271-01 Hendricks (PI) 05/01/08-04/30/13
NIH/NEI
Interdisciplinary Visual Sciences Training Program
Provides support for graduate student and postdoctoral training in visual sciences

R01 EY10359-17 Hendricks (PI) 12/01/93-12/31/11
"Cytokines and Adhesion Molecules in HSV Keratitis"
The goal of this study is to examine the mechanisms of immunopathology in herpes simplex virus type 1 infected corneas.

R01 EY05945-24 Hendricks (PI) 12/30/86-12/31/13
"Cytotoxic Lymphocytes and HSV-1 Corneal Lesions"
The goal of this study is to investigate the role of the immune system in controlling HSV-1 latency in sensory ganglia.
 
 
  Top of page  |  Home  |  Contact Us Last Update 3/27/2017  
  © Office of the Senior Vice Chancellor for the Health Sciences, University of Pittsburgh. All rights reserved.